Built an app to show how Rentosertib actually works. 🧬✨
It recently showed an anti-aging effect in clinical trials. 👀
GPT-6 Astra again. The crazy part: ~40 minutes to build, plus an MD simulation 🤯
@Derya_tm @EvgenyKirilin, this really feels like a new level of structural analysis.
Rentosertib inhibits TNIK, a kinase and one of the molecular switches controlling signaling inside our cells. ⚙️ Kinase activity is also exactly the kind of property Insilico Medicine’s models are built to predict. 🤖🔬
#insilicoSOTAFM
Learning
How the drug Rentosertib inhibits TNIK, as an app built in 40 minutes
Andrew Aiginin, a generative biologics product manager at Insilico Medicine, used GPT-6 Astra to build an app explaining how Rentosertib, a drug that recently showed an anti-ageing effect in trials, switches off the TNIK kinase. It took about 40 minutes plus a molecular dynamics simulation.
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- Made with
- GPT-6 Astra
- Role
- Generative biologics product manager, Insilico Medicine
- Posted
