Science Professionals

A ChatGPT-designed schizophrenia drug, synthesized in a garage lab

Douglas Yao, a former Harvard computational biology PhD who now makes drugs, had ChatGPT design PAC-3310, a selective M4 muscarinic receptor agonist for schizophrenia, then synthesized the compound in a chemistry lab built in their garage.

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ChatGPT
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Drug developer, formerly a computational biology PhD at Harvard
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Douglas Yao@DouglasYaoDY

This vial contains a new drug called PAC-3310. It was designed by ChatGPT, and I synthesized it in a chemistry lab I built in my garage.

PAC-3310 is a new selective M4 muscarinic receptor agonist for treating schizophrenia - similar to the recent breakthrough drug Cobenfry, but improved. (1/7)

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